Tuesday, July 26, 2016

Statins prevent repairs in the body....

Today's Post:  Tuesday, 7-26-2016

This somehow missed being headline news when the study it was in appeared about a year ago in late July, 2015:

“Statins prevent repairs in the body!”

1.  You may have read that there are initial experiments showing that stem cells have been found in small scale experiments to heal the damage from nonfatal heart attacks well enough to prevent or even reverse impairment of the person’s lifestyle or heart failure or even both!

The evidence is that it repairs the damage caused by the heart attack or enough of it to preserve function.

You may also have read that when younger people lose their stem cells and their stem cell’s ability to make and use cells as which they tend to do as they get older, this is one of the reasons people develop diseases and become more limited and closer to death with increasing age.

So, such treatments using stem cells and exercise that prevent or reverse this decline in stem cells and repairs all over the body are a key way to slow aging and keep good health. 

It’s been known for quite some time that statins reduce the level of ubiquinol, the form of CoQ10 that the body uses.  And, it’s been known that this weakens the mitochondria that provide the power for each of our cells.

This weakens the heart by depriving it of energy on a cellular level.  In many people, this also makes them less energetic and feel low on energy or much older. 

But what if statins also reduced the ability of the body to make and use stem cells for repair too?

That research has apparently been done over a year ago.  It found that statins also reduced the ability of the body to make and use stem cells for repair. 

I just got this in their email; and here is the link to their story:

Here are some key quotes:

The study, which was published in the American Journal of Physiology, states that statins’ “…impact on other biologic properties of stem cells provides a novel explanation for their adverse clinical effects.”

Specifically, the study states that such adverse effects include advancing the “process of aging” and also notes that “…long-term use of statins has been associated with adverse effects including myopathy, neurological side effects and an increased risk of diabetes.”

“….those taking such cholesterol-lowering drugs have been experiencing cataracts, fatigue, liver problems, muscle pain and memory loss. Simply put, the drugs have been found to tamper with cells in such a way that their primary purpose of reproducing and helping the body repair is thwarted. With that comes the onset of terrible health issues or the worsening of existing ones.”

“Professor Reza Izadpanah, a stem cell biologist and lead author of the published study, says,
“Our study shows statins may speed up the ageing process.

People who use statins as a preventative medicine for [health] should think again as our research shows they may have general unwanted effects on the body which could include muscle pain, nerve problems and joint problems.”

2.  For some time it has been clear that there are much more effective ways to prevent heart attacks, prevent fatal heart attacks, and even lower LDL cholesterol and chronic inflammation than taking statins. 

The comparison is not close either, the alternatives are better by 20 times or more and even are effective when statins have zero effect!

It’s also known that only about 35% of people have the genetics that make statins even reduce the number of nonfatal heart attacks at all well and that there is a test cardiologist Arthur Agatson, MD says can tell which heredity a person has for about $150. 

Most doctors today still prescribe statins instead of the more effective methods and hardly any do this test first.

That’s because statins are the only thing they know that might help that they can prescribe or they are following guidelines that factor in none of this knowledge.

Here’s why I think statins should never be prescribed or taken at all with very rare exceptions:

a)  Why not prescribe things that are more effective and reduce the death rate from heart attacks and all causes AND have other health benefits instead? 

(They exist and have been tested to work; and I’ve posted on them and use them personally.)

b) But even without that, the track record of harm from statins is so severe that in my view it is irresponsible or worse to prescribe them.

Here’s why:

*Regular vigorous exercise done most days of every week slows aging and prevents disease – including heart attacks and deaths from them in people who build up to more vigorous levels. 

And regular vigorous exercise done most days of every week keeps working better and better for heart protection the more consecutive years people do them research has found!

Giving such people statins is quite dangerous studies found! 

The more vigorous the exercises are done, the more heart protective they are.  But if they take statins, the more vigorously those people exercise, the more likely it is they will PERMANENTLY harm their muscles.

Secondly, gradually improving your ability to exercise strengthens your heart and makes you more physically able.  But people who take statins do not get that effect. The statins prevent it.

Given these two facts alone, statins should be limited to bedridden patients if they are ever used at all. 

And, no statins should ever be prescribed until the genetic test is done and the person tests to be in the 35% that get some protection from them.

*Secondly, type 2 diabetes increases the death rate from heart attacks and has been shown to harm circulation all over the body and directly cause Alzheimer’s disease in addition to speeding the process from the drop in circulation the diabetes causes.

(If blood sugar is where it should be your insulin helps in cleaning your brain and removing things like beta amyloid.  But if blood sugar is too high, the insulin deals with that instead and stops the brain cleaning.  This then results in beta amyloid build up which can get to the hard to reverse stage.)

It’s expensive to treat thousands of people for type 2 diabetes as well.  So it’s highly undesirable to increase the number of people who have type 2 diabetes when it can be avoided.

The news is in and has been for some time. 

Taking statins causes type 2 diabetes in people who take it.

A study that is quoted found this happens 9% of the time.  And, I remember seeing one that was much higher, 45% I think.

Type 2 diabetes is so harmful to the heart and increases heart attack risk about double for men and four times for women that this is likely why at least one reason statins show no reduction in fatal heart attacks.

So this too is a big enough and a well known enough reason to never use statins when more protective methods exist.

Then too many of the alternative methods to prevent heart attacks also PREVENT type 2 diabetes!

*Another study found that taking statins caused cataracts in about 3% of the people taking them who would have avoided them or gotten them years later.

If statins were far more protective than that, they might be justified.  But added to the two big reasons not to use them, it’s not at all justified to cause people to take statins.

But while the first two reasons might be fixable by taking a large amount of ubiquinol since they initially seemed to be caused by the harm to the mitochondria which taking enough ubiquinol might prevent, what I’ve wondered, might be causing cataracts?

This recent study is so hugely important because it likely shows why statins cause cataracts.

AND it’s important because it shows that taking ubiquinol may NOT be effective at preventing the first two effects!

Exercise causes fitness and protects your heart when AFTER the exercise, your body repairs and even over repairs the muscles you used.  Vigorous exercise has even been found to increase stem cells!

But if the stem cells you would have had more of by exercising to do this are less instead or don’t work because of taking statin drugs, taking statin drugs will cause this harm or almost as much of it even if you replace the ubiquinol.

Similarly type 2 diabetes depends on processes in the liver and pancreas working well. 

If they stop doing so since they are no longer repaired by the stem cells that statins removed or harmed, that would also explain why taking statins has such a dreadfully high rate of causing type 2 diabetes.

This too suggests that replacing the ubiquinol the statins removed might not prevent this either!

Here’s the summary of how to prevent heart disease that also prevents deaths from heart disease:

Eat 6 or more servings of organic vegetables a day or as close to that as you can manage.
This has been shown to slam down the death rate from heart disease by 24%.

Totally stop eating and drinking heart attack starters!

(Taking anything to stop a disease you keep causing to happen is nuts, craziness, and worse!)

 These include high fructose corn syrup and artificial sweeteners and the soft drinks that contain them! It also includes ANY hybrid wheat and even eating more than sparing consumption of other whole grains.  It also includes any hydrogenated oils. (Eating small, regular amounts builds up in your body to very harmful levels.  So, the only safe intake of hydrogenated oils is zero.)

Related to this is staying 100 % away from tobacco and its smokeEvery exposure begins to close your blood vessels.  And, we also now know that exposure to tobacco smoke triggers heart attacks in people who would not have had them otherwise!

Having done that, begin at a very easy level to do regular vigorous exercise most days of every week. Then gradually build up to more vigorous levels. 

Lastly, there is a very large list of foods, herbs, and supplements that cut your risk of heart disease to close to zero if you do these basic things first

The omega 3 oil, DHA; and niacin; and ginger; and turmeric and/or curcumin supplements from turmeric; CAN do and have long been known to do the things statins do that are beneficial better than statins do.  And, instead of horrid side effects, they have other health benefits.


To get more detail about this study, I entered this in Google:

“American Journal of Physiology AND Reza Izadpanah”

Several things appeared including the original study.

This one I thought included some of the most compelling information so I quote from it below.


"For the research, which was reported in the American Journal of Physiology on July 29, (2015) Izadpanah and colleagues treated stem cells with statins in the lab. After several weeks, they found that treatment with the drug had dramatic effect.
The researchers discovered that the drug prevented the stem cells from reproducing and replicating the body's cells to repair damage.
"Statins impair the osteogenic and chondrogenic differentiation potential of Mesenchymal Stem Cells (MSCs), increase cell senescence and apoptosis," the researchers wrote in their study. "Statins also impaired the expression of DNA repair genes including XRCC4, XRCC6, and Apex1."

Izadpanah and his colleagues said that given the unwanted effects of the drug, people should be completely informed of the risks prior to starting with the treatment.”  

Labels: , ,


Post a Comment

<< Home