Tuesday, July 19, 2016

Alzheimer’s Prevention News....

Today's Post:  Tuesday, 7-19-2016

We already know that Alzheimer’s is very close to fully preventable.

You can do the things that prevent heart disease including regular vigorous exercise and keeping the amount of small particle LDL low and keeping systemic inflammation low.

The regular vigorous exercise releases BDNF a hormone that grows new nerves and brain cells which has been shown to prevent decreases in the white matter that allows your brain to communicate between its parts—including the hippocampus which contains your memory center.

The low inflammation lifestyle that is heart protective also prevents Alzheimer’s disease.

NOT ingesting wheat and high fructose corn syrup and grain oils or fat from
factory farmed animals fed grains AND eating omega 3 oils from wild caught fish and taking omega 3 supplements and DHA AND taking curcumin and ginger or using turmeric and ginger as spices often EACH lower small particle LDL AND lower chronic inflammation BOTH of which prevent Alzheimer’s disease from forming or reverse it in its early stages.

Taking stigmasterol along with beta sitosterol that usually appears with it is well known in research circles to remove beta amyloid plaques. And, in fact, taking it has restored the sense of smell in people who have lost it due to beta amyloid deposits.

Recent news:

1.  More evidence that lack of exercise is a key cause of Alzheimer's disease:

The researchers found that, contrary to previous understanding, the first physiological sign of Alzheimer's disease is a decrease in blood flow in the brain. An increase in amyloid protein was considered to be the first detectable sign of Alzheimer's.

Lack of exercise reduces blood flow to the brain.  It also reduces the amount of BDNF that grows new brain cell and nerve cells.

Lack of exercise also helps cause high blood sugar which we now know causes insulin to be used more to combat high blood sugar and less to clear beta amyloid thus causing it to build up over time.

Of course exposure to tobacco smoke and eating and drinking too much sugar and other heart attack starters and NOT getting enough omega 3 oils also cuts blood flow to the brain.  (The cadmium in tobacco smoke also boosts the rate of Alzheimer's by another 50%.)

Big Data' study discovers earliest sign of Alzheimer's development
Scientists at the Montreal Neurological Institute and Hospital have used a powerful tool to better understand the progression of late-onset Alzheimer's disease (LOAD), identifying its first...
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From: Medical News Today
To: iehealth
Sent: Thu, Jul 14, 2016 2:03 pm
Subject: MNT daily newsletter - 14 July 2016  

2.  Ingesting enough DHA prevents brain shrinkage even without exercise by releasing BDNF.

(Doing both releases more.)

Recently Al Sears MD sent an email with this:

"....as you age, some brain regions shrink at a rate of 0.5% per year?
The loss in volume of grey matter is the leading contributor to weaker brain function in the elderly.
That’s especially the case in the brain’s hippocampus — our memory and learning center.
But a team of UCLA researchers....gave (DHA) to a group of 265 men and women over the age of 65 once each week.
Then they analyzed the MRI scans of their brains.
Their brain’s hippocampus was 14% larger than the placebo group!

That’s how much the average brain declines over the course of 28 years. In other words..."Their Brains Got 28 Years Younger""

In other words, the regular, vigorous exercise keeps you hippocampus at full size and operational plus keeping the white matter wiring to it intact.

Apparently so does getting enough DHA.  And of course the ideal is to do both.

3.  For women, taking bioidentical estrogen at menopause not only relieves symptoms, research found it reduces the development of Alzheimer’s disease.

Medical News Today recently had this:

"Newly postmenopausal women who received estrogen via a skin patch had reduced beta-amyloid deposits, the sticky plaques found in the brains of people with Alzheimer's disease, a Mayo Clinic study published this month in the Journal of Alzheimer's Disease found. Ultimately, these deposits harm neurons, leading to cognitive problems.

In the study, women with APOE e4 - one form of the most common gene associated with late-onset Alzheimer's disease - had lower levels of amyloid deposits.

"This study showed, for the first time, that the brain amyloid deposition - a hallmark of Alzheimer's disease - is reduced in newly postmenopausal women who received 17 beta-Estradiol patch form of hormone therapy," says lead author Kejal Kantarci, M.D., a Mayo Clinic radiologist. "Women with APOE e4, who have a greater genetic risk for Alzheimer's disease, particularly benefited from this therapy."

Estrogen patch in newly postmenopausal women may reduce Alzheimer's risk
Can estrogen preserve brain function and decrease the risk of Alzheimer's disease when given early in menopause?

-----Original Message-----
From: Medical News Today
To: iehealth
Sent: Thu, Jul 14, 2016 2:03 pm
Subject: MNT daily newsletter - 14 July 2016  "

(This patch delivers the FDA approved bioidentical estrogen – NOT the pill based on horse hormones that caused all the problems that caused women to stop using it.

Also, I’ve read some evidence that the low chronic inflammation lifestyle ALSO may make even that form safe to take and almost certainly makes the real hormone safe to take.

Since that lifestyle also prevents Alzheimer’s, doing both is likely quite very protective!

4.  Taking cinnamon as a supplement and using it often as a spice also prevents Alzheimer’s 3 ways!

a) If you take cinnamon before eating a sugary treat of some kind or use it as a spice in the dish itself, your blood sugar surges considerably less.

This leaves more insulin available to clear beta amyloid where without the cinnamon the insulin would be clearing the sugar instead.

b)  Sugars in your blood can bind to proteins in a process called glycation.  In blood vessels this can reduce blood circulation to your brain causing more Alzheimer’s development.  Cinnamon also reduces glycation and helps prevent this.

c)  Sunday this past weekend Medical News Today also had research showing that cinnamon enabled better hippocampus function and better learning when they were slowed.

Cinnamon boosts learning in the hippocampus and can improve learning capacity!

Cinnamon: Could this popular spice make us better learners?
A sprinkle of cinnamon on your breakfast could be the difference between being a good learner or a bad learner, mouse study concludes.

-----Original Message-----
From: Medical News Today
To: iehealth
Sent: Sun, Jul 17, 2016 1:37 pm
Subject: MNT daily newsletter - 17 July 2016

5.  What if there was so much beta amyloid build up, the resulting later stage of Alzheimer’s looked irreversible by the methods we just listed.?

That would look pretty dire.  People who get that far into it even die. 

It’s still not available here as far as I know, but there IS now at least one way to reverse this.

The initial news I read sounded like some kind of electronic pulse was used.

Last week I got the exact reference.  It DOES work and uses ultrasound in focused pulses.

The health freedom newsletter had this: 


The most effective treatment for Alzheimer’s Disease is gaining more notoriety and it’s drug-free. University of Queensland researchers have confirmed that non-invasive ultrasound technology breaks apart the neurotoxic amyloid plaques that result in memory loss and cognitive decline.

I then found this:


“New Alzheimer’s treatment fully restores memory function   Of the mice that received the treatment, 75 percent got their memory function back.”

“Publishing in Science Translational Medicine, the team describes the technique as using a particular type of ultrasound called a focused therapeutic ultrasound, which non-invasively beams sound waves into the brain tissue. By oscillating super-fast, these sound waves are able to gently open up the blood-brain barrier, which is a layer that protects the brain against bacteria, and stimulate the brain’s microglial cells to activate. Microglial cells are basically waste-removal cells, so they’re able to clear out the toxic beta-amyloid clumps that are responsible for the worst symptoms of Alzheimer’s.

The team reports fully restoring the memory function of 75 percent of the mice they tested it on, with zero damage to the surrounding brain tissue. They found that the treated mice displayed improved performance in three memory tasks - a maze, a test to get them to recognise new objects, and one to get them to remember the places they should avoid.”

Clearly if the other things that restore memory and brain cells are done and the things like taking stigmasterol that also remove beta amyloid are done, the potential of the combined actions looks likely to get more like a 95% reversal rate.

There is evidence for this too.  A UCLA team used some of these other methods in combination in a small study with people and got close to a 90% reversal rate.

(Mathematically, if your reverse mental decline in 75% of the people and then 90% of the remaining 25%, the overall reversal rate would be 97.5%

Given the several things we already know work that I’ve not listed here could be added too,

-- we are indeed approaching a reversal rate that is closing in on 100%.  

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